COSIS is the acronym for Combined DNA Index System. It is a software program that operates national, state, and local level databases of DNA profiles from convicted offenders and missing persons. It also stores DNA profiles of unsolved crime scene evidence. It is basically a DNA database that stores information gained from crime labs in the U.S.
In the U.S., each state has a statutory provision for the establishment of a DNA database that provides for the collection of DNA profiles from offenders convicted of particular crimes. CODIS is funded by the U.S. Federal Bureau of Investigation.